IV Ketamine Shows Potential Promise for Refractory Headache in Children

A recent report suggests IV ketamine may be "promising for severe refractory headache in children." This is promising, but a word of caution at the end...

According to findings reported in a meeting (April 15) at the American Academy of Neurology, "IV ketamine led to a 50% reduction in pain at discharge, with nearly 2/3 of patients having no recurrence within 30 days."

The Study:
The retrospective study analyzed 68 treatment sessions involving 41 patients aged 5-21 years, predominantly girls with chronic migraine without aura. Patients were administered a median dose of 0.25 mg/kg/hr of IV ketamine over a median duration of 3 days.

The Findings:
Approximately 50% reduction in pain scores at discharge, and two-thirds of patients experienced no headache recurrence within 30 days.

While this research is promising, it's imperative to be exceedingly cautious when utilizing pharmaceuticals with and for adolescents. I firmly believe that, while these treatments can offer significant relief and represent a major advancement in pediatric care, they should ideally be considered when other integrative approaches have been explored.

Prioritizing nutrition, lifestyle adjustments, and other non-pharmacological therapies can often provide foundational support for the young patient's health.

It's only when these avenues have been thoroughly explored and if symptoms persist, it is then that we might consider advanced pharmaceutical interventions. Ensuring a balanced approach that prioritizes the overall well-being and long-term health of children is essential

Link to the report here.