The tragic passing of Matthew Perry highlights critical missteps in the administration of ketamine, underscoring the necessity for stringent ethical standards and proper patient care in medical practice. This analysis breaks down the key areas where Perry's treatment deviated from acceptable medical practices.

Dr. Weiner reviews a recently published deep dive into ketamine's use as a rapid antidepressant, exploring its potential and pitfalls and highlighting therapeutic effects, ethical concerns, and safety issues in treatment-resistant depression.