Dr. Weiner explores a recently published secondary analysis of a trial that compared ketamine to electroconvulsive therapy (ECT) for treatment-resistant depression, finding that ECT and ketam!ne both effective long-term, with moderate to severe depression patients having faster improvement with ketamine, and very severe depression responding faster to ECT.

Dr. Weiner reviews a recently published deep dive into ketamine's use as a rapid antidepressant, exploring its potential and pitfalls and highlighting therapeutic effects, ethical concerns, and safety issues in treatment-resistant depression.

New (May 2024) research unveils the mechanisms behind ketamine's ability to induce altered brain oscillations, offering profound insights into its therapeutic potential and the nature of consciousness itself.